The deal on wheels as it pertains to Isuzu vehicles.
When I bought my Trooper, it had a set of 18" American Racing chrome wheels on it with 285/60-18 Yokohama AVS/ST tires on them.
It looked super cool, but I didn't want to give the dealership the $2500 they wanted for the combo. I could have replaced that combo through just about any place online for around $1600.
Anyway, the 18s looked sweet, especially since the backspacing stuck them out a little bit, increasing the track, which increased the stability, but it also increased the torque steer and kickback.
The further you put the tires from the center of the vehicle, the more it will wear on your bearings in a way that they weren't designed for. It will also drastically affect your steering. It will require more effort, you'll feel more potholes, and imperfections and things like that, and if there is a rut in the road, it will really want to follow it.
I've had my eye on a set of 20" Enkei RT6s for some time. Streetdreams.org has them for $190 each, which is way cheap. Nobody would be able to sell me on going with a bigger wheel than a 20", at least on an Isuzu, unless they were free or REEEEAALLY cheap.
With a 20" wheel, they still look sweet, but they still have some sidewall, which brings me to my final point.
If your VX rides anything at all like my Trooper, it's not the smoothest thing in the world.
To break it down on a scale of one to ten, if riding in a Lincoln is like a 1, and riding on a lawn tractor over a really crappy trail is a ten (also, a ten would be a roller coaster), if you put 22s or bigger on your VX, it's going to ride somewhere around a 7-8.
It'll ride like crap, is my point. Plus, you have less sidewall to protect the wheel from flubs on the road that cause curb rash, pothole damage, and things like that.
Go with 22s if you want, but be forewarned.
18-20" is a good size to look cool but stay practical.
As a final note: For God's sake, please keep your factory wheels and tires for winter and/or trail riding! I see people all over town running around on their dubs in the snow. Real smart.