As others have said, and as with ANY used car purchase, it'll come down to "the luck of the draw". I bought close to six years ago from an original high desert owner with 58K miles on the clock, and a non-op driver's side window. My buddy took the door panel off, "tweaked" the OEM brackets, and put the door panel back on - it's been working PERFECTLY ever since! I've put 51K miles on mine, with boringly consistent oil consumption of 1 quart every 4K miles; other than the timing belt/water pump replacement at 100K, a power steering pump, and a radiator (which it didn't even NEED), mine has run like a Swiss watch - hell, it still has the original shocks & brake pads! It's my daily driver for six years now, and I would not hesitate to drive it cross country TOMORROW; having said that, I realize that my VX has been "the exception to the rule" - negligible oil consumption, no window issues, no TOD issues, no ABS module issues...
Don't forget too - Isuzu is an "orphan" here in the USA now; before *I* would consider buying one, I would be CERTAIN that I had a competent local "wrench" that I felt confident about working on same first. Good luck w/your decision!