I have noticed that Driving on the interstate with power mode on is a nightmare, it always downshifts to climb even the weakest hill, but in normal operation it would hold the gear and the speed. The needless down shifts leed to needless high revs that would cause more wear on the motor and tranny.
Not to mention i found i get better fuel mileage in normal on the interstate vs power mode. I do however drive the vx up to Rausch Creek and down to Ky often, both trips have some long steep climbs.
In the city however I always leave it in power.