Simple............"frontal crash safety"; and resulting lawsuits/liability against the manufacturer's, but I'm sure aerodynamics also played a role in improving MPG. How many Cab-Over design semi-tractor trailer big-rigs do you see on the freeways nowadays???
The coolest cabover design pick-up ever created was the Hot Wheels "Deora" from 1967/1968 era with the surf boards.
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