I've had mine for just over a year now and although I've had problems with it I'd buy another tomorrow.
As has been said, mechanical parts are easy to get. Body parts are a constant source of worry, but I'll cross that bridge if (hopefully never!) I come to it!
The problems I've had have both been electrical - One was a small 'g sensor' fitted under the truck near the fuel tank. It went faulty and caused the VX to stutter and stall. Took weeks to narrow the fault down and when I did, took several more to find the part. But thanks to the guys 'n' gals on here, I got the part and shipped to the UK for just over $100.
The other fault is the drivers door window switch. It also controls the central locking so that didn't work, nor did the windows. Being RHD, the part is onlt available from Isuzu and isn't used on any other vehicles - cost = $500
So as I said - love the truck and would get another, but the ability to source the rarer parts does concern!
Nick