It may be possible to remove the panel with the door shut, but there is also the possibility of cracking or breaking the panel or plastic "carbon fiber" inserts. I decided to take the risk vs. never using the driver's door again. I was "lucky" because my door was latched but not completely shut. After removing the screws, I was able to pop all the nylon retainers. I'm sure the retainers were somewhat worn since the panel had been removed at least 3 times before the lock broke. I couldn't get to the screw to remove the tweeter cover, but was able to slide the panel toward the back to slip it out from underneath the cover. Then it was a matter of sliding/rotating the panel back & up while sitting in the back seat. It also involved moving the front seat backward / forward and reclining / pushing forward the backrest as needed. Sounds like a lot, but it took about 3 - 4 minutes.