Beauty is in the hand of the gun-holder... I tried Glocks, Rugers, S&W's, Berettas, etc. and never found one that seemed to properly fit my hand. When I first picked up an HK USP .40 at a gun show in MO, I knew that was the one. The tang fit my hand like no other ever had. It took a couple of years, but I ended up getting one.
As for Glocks - YMMV! I know a lot of people swear by them, and there are plenty of cases of flawless operation for thousands of rounds, but I've also seen too many of them jam (and really, ONE is too many!). At my cousin's bachelor party, two guys brought their Glocks (a 9 mm and a .40) to the firing range where we started the day (and oh, waht a day that was!), and BOTH of them jammed up. WTF?!?! I find that completely unacceptable - if I owned a gun that jammed even once, I'd sell it.