The fabled GM motor swap??
This idea has been talked about and kicked around by several VX owners. When my engine blew in Nov. this year I looked into the possibility of dropping a GM crate engine into mine instead of using the factory Isuzu motor. I was only looking to use the GM engine and not the drivetrain as you are suggesting. Here are some things to consider:
Engine placement & mounts--lots of custom fabricating
Wiring--not as easy as just replacing the ECM and factory wiring
Accesories--custom mounts for AC, Alt., and oil pump
Now for the tranny:
Again custom mounts and location
Custom drivelines
This project is borderline insane. Not to mention the custom fab and wiring headaches, the cost is could be more than your VX is worth. Easily 10-15 grand USD and you're in Canada. If you go through with this swap my hat comes off to you. Just keep all notes for the custom made parts to make this available to anyone else that would like a different powerplant. Good luck.